Why You Always in a Mood? Pumpin’ Polyp, Actin’ Brand New

NEURON(2022)

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摘要
What causes neurons to die in neurodegenerative disease? In this issue of Neuron, Arredondo et al., 2022 report an unexpected culprit that may drive neuronal death in amyotrophic lateral sclerosis-an evolutionarily ancient energy-storage polymer called polyphosphate (polyP).
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