Three-dimensional hydrogel culture systems support growth and determination of chemosensitivity of feline sarcoma and carcinoma cell lines.

Jacqueline V J Cavalcanti,Kimberly A Selting,Mai T Ngo, Christine K Tran Hoang,David J Schaeffer,Timothy M Fan,Brendan A C Harley,Heidi Phillips

American journal of veterinary research（2022）

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摘要

3-D hydrogel cell culture systems supported growth of feline tumor cells for determination of in vitro chemosensitivity. IC50s of each cell line were within the range of carboplatin concentrations eluted from C-ICSH beads. Cells from FISAS and FOSCC cell lines treated with carboplatin showed dose-dependent and time-dependent decreases in viability.

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关键词

feline sarcoma,cell lines,chemosensitivity,three-dimensional

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