Linezolid for patients with multidrug-resistant tuberculosis/extensively drug-resistant tuberculosis in China Comment

DRUG DISCOVERIES AND THERAPEUTICS(2022)

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Abstract
Linezolid has been one of the key anti-tuberculosis agents for the treatment of multidrug-resistant tuberculosis (MDR-TB)/extensively drug-resistant tuberculosis (XDR-TB). It used to be very expensive and was not covered by social insurance from local governments. Nevertheless, a growing number of patients in China received linezolid in their anti-MDR/XDR TB regimens over the past decade. Many scholars in China have reported their experience using linezolid to treat patients with MDR/XDR-TB. In view of this, existing evidence of the efficacy and safety of linezolid and problems faced by Chinese patients with MDR/XDR-TB are summarized here.
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Key words
Linezolid, MDR, XDR-TB, China, drug resistance
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