Efficient Human-Like Antibody Repertoire and Hybridoma Production in Trans-Chromosomic Mice Carrying Megabase-Sized Human Immunoglobulin Loci

Hiroyuki Satofuka,Satoshi Abe,Takashi Moriwaki,Akane Okada,Kanako Kazuki,Hiroshi Tanaka,Kyotaro Yamazaki,Genki Hichiwa,Kayoko Morimoto,Haruka Takayama,Yuji Nakayama,Shinya Hatano,Yutaro Yada,Yasufumi Murakami,Yoshihiro Baba,Mitsuo Oshimura,Kazuma Tomizuka,Yasuhiro Kazuki

Nature communications（2022）

引用 9|浏览34

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关键词

Antibodies,Antibody generation,Genetic engineering,Immunogenetics,Science,Humanities and Social Sciences,multidisciplinary

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