A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children.

A Laura Nijstad,Evelien de Vos-Kerkhof,Catherine F Enters-Weijnen,Marianne D van de Wetering,Wim J E Tissing,Lidwien M Hanff, Rogier Lange,Matthijs M Tibben,Hilde Rosing,Arief Lalmohamed,C Michel Zwaan,Alwin D R Huitema

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners（2022）

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摘要

Our extemporaneous oral suspension is an adequate alternative for the commercially (un)available oral suspension in young children. An adequate exposure to aprepitant in children was yielded and the bioavailability of the extemporaneous suspension was comparable to capsules.

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关键词

Oncology,Pediatrics,Pharmacokinetics,Pharmacology

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