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Development of Novel Urea-Based ATM Kinase Inhibitors with Subnanomolar Cellular Potency and High Kinome Selectivity.

Teodor Dimitrov, Cetin Anli,Athina Anastasia Moschopoulou,Thales Kronenberger,Mark Kudolo,Christian Geibel,Martin Peter Schwalm,Stefan Knapp,Lars Zender,Michael Forster,Stefan Laufer

European journal of medicinal chemistry（2022）

引用 4|浏览19
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关键词
ATM kinase,ATM kinase inhibitors,MD simulation,DDR pathway,Cancer,PIKK
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