Identification of a Novel SARS-CoV-2 Delta-Omicron Recombinant Virus in the United States

Kristine A. Lacek,Benjamin L. Rambo-Martin,Dhwani Batra,Xiao-yu Zheng, Hitoshi Sakaguchi,Thomas Peacock,Matthew Keller,Malania M. Wilson,Mili Sheth,Morgan L. Davis,Mark Borroughs,Jonathan Gerhart,Norman Hassell,Samuel S. Shepard,Peter W. Cook,Justin Lee,David E. Wentworth,John R. Barnes,Rebecca Kondor,Clinton R. Paden

biorxiv（2022）

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摘要

Recombination between SARS-CoV-2 virus variants can result in different viral properties (e.g., infectiousness or pathogenicity). In this report, we describe viruses with recombinant genomes containing signature mutations from Delta and Omicron variants. These genomes are the first evidence for a Delta-Omicron hybrid Spike protein in the United States.### Competing Interest StatementThe authors have declared no competing interest.

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