Chronic Kidney Disease in Patients After Allogeneic Hematopoietic Cell Transplant

Transplantation Proceedings(2022)

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摘要
•Kidney damage remains significant complication of hematopoietic cell transplant affecting the mortality of transplant recipients.•Chronic graft-vs-host disease is common, and serious complication of allogeneic hematopoietic cell transplant occurs in about 60% to 80% of patients.•A total of 30% to 60% of patients with acute graft-vs-host disease progressed to chronic disease, with about 20% requiring lifelong immunosuppressive therapy that had toxic effects on kidney function.•It is very important to consider a comprehensive approach to develop and update treatment regimens and constantly monitor drug levels.
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关键词
allogeneic hematopoietic cell transplant,chronic kidney disease
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