Very Rare Near‐haploid Acute Lymphoblastic Leukemia Resistant to Immunotherapy and CAR‐T Therapy in 19‐year‐old Male Patient

Tomas Arpas,Hana Jelinkova,Stepan Hrabovsky,Martina Orsulova,Zuzana Vrzalova,Veronika Navrkalova,Eva Brhelova,Lenka Bryjova,Alena Bulikova,Eva Ondrouskova,Marketa Sejnohova,Frantisek Folber,Petra Sedova,Jiri Mayer,Sarka Pospisilova,Marie Jarosova,Michael Doubek

Clinical case reports（2022）

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摘要

Near-haploid acute lymphoblastic leukemia is rare subgroup of the disease, which is very important due to very poor prognosis and resistance to treatment including novel monoclonal antibodies and CAR-T therapy.

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关键词

acute lymphoblastic leukemia,blinatumomab,CAR-T therapy,inotuzumab ozogamicin,near-haploid

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