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A Trem2R47H Mouse Model Without Cryptic Splicing Drives Age- and Disease-Dependent Tissue Damage and Synaptic Loss in Response to Plaques

Kristine M. Tran,Shimako Kawauchi,Enikö A. Kramár,Narges Rezaie, Heidi Yahan Liang,Jasmine S. Sakr,Angela Gomez-Arboledas,Miguel A. Arreola,Celia da Cunha,Jimmy Phan,Shuling Wang,Sherilyn Collins,Amber Walker,Kai-Xuan Shi,Jonathan Neumann, Ghassan Filimban,Zechuan Shi,Giedre Milinkeviciute,Dominic I. Javonillo,Katelynn Tran,Magdalena Gantuz,Stefania Forner,Vivek Swarup,Andrea J. Tenner,Frank M. LaFerla,Marcelo A. Wood,Ali Mortazavi,Grant R. MacGregor,Kim N. Green

Molecular neurodegeneration（2023）

Cited 2|Views32
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Key words
Alzheimer’s Disease,Microglia,Inflammation,TREM2 R47H,MODEL-AD,LTP
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