Impact of Short-Term Storage on Ex Vivo Antimalarial Susceptibilities of Fresh Ugandan Plasmodium Falciparum Isolates

Martin Okitwi,Stephen Orena,Katairo Thomas,Patrick K. Tumwebaze,Oswald Byaruhanga,Samuel L. Nsobya,Melissa D. Conrad,Brett R. Bayles,Philip J. Rosenthal,Roland A. Cooper

Antimicrobial agents and chemotherapy（2022）

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摘要

We measured susceptibilities of Ugandan Plasmodium falciparum isolates assayed on the day of collection or after storage at 4°C. Samples were incubated with serial dilutions of 8 antimalarials, and susceptibilities were determined from 72-h growth inhibition assays.

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关键词

Plasmodium falciparum,Uganda,antimalarials,cold storage,drug susceptibility,ex vivo,growth,malaria

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