Overexpression of Ubiquitous Mitochondrial Creatine Kinase Denotes a Worse Prognosis for Gastric Cancer Patients

Senlin Zhao,Junyong Weng,Ying Liu,Yongjie Wang, Zhipeng Yang, Shuo Zhang,Huimin Sun,Yugang Wen,Yushuai Mi

Social Science Research Network（2018）

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摘要

Background: Ubiquitous mitochondrial creatine kinase (uMtCK) transfers high-energy phosphates from mitochondrially generated ATP to creatine to generate phosphocreatine. uMtCK overexpression has been reported in several malignant tumours, however, the clinical significance of uMtCK in gastric cancer (GC) has not been comprehensively studied.

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