Plasma Phosphorylated Neurofilament Heavy Chain (Pnf-H) Level is Associated with Future Motor Function in Nusinersen-treated Individuals with Later-onset Spinal Muscular Atrophy (SMA) (2248)

Michelle A. Farrar,Francesco Muntoni,Charlotte J. Sumner,Thomas O. Crawford,Richard S. Finkel,Eugenio Mercuri,Xiaotong Jiang,Jihee Sohn,Marco Petrillo, Steve Garafalo,Wildon Farwell

Neurology（2021）

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摘要

To evaluate the association between plasma phosphorylated neurofilament heavy chain (pNF-H) levels and clinical motor function endpoints in nusinersen-treated individuals with later-onset spinal muscular atrophy (SMA) who participated in the CHERISH/SHINE studies.

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