Paranoide Psychosen bei HIV-Infektion

Paranoid psychosis developed in two homosexual patients (aged 36 and 37 years) three and four years, respectively, after found to have an HIV infection. There was a marked reduction in the T-helper to T-suppressor-cell proportion (0.4 and 0.2). Neither computed tomography nor magnetic resonance imaging, nor microscopic, microbiological and biochemical tests of cerebrospinal fluid demonstrated opportunistic infection of the central nervous system. After treatment with haloperidol (3 mg daily) there was a rapid regression of the psychotic symptoms.