Gene Editing Reverses Arrhythmia Susceptibility in Humanized PLN-R14del Mice: Modelling a European Cardiomyopathy with Global Impact.
Jaydev Dave,Nour Raad,Nishka Mittal,Lu Zhang,Anthony Fargnoli,Jae Gyun Oh,Maria Elisabetta Savoia,Jens Hansen,Marika Fava,Xiaoke Yin,Konstantinos Theofilatos,Delaine Ceholski,Erik Kohlbrenner,Dongtak Jeong,Lauren Wills,Mathieu Nonnenmacher,Kobra Haghighi,Kevin D. Costa,Irene C. Turnbull,Manuel Mayr,Chen-Leng Cai,Evangelia G. Kranias,Fadi G. Akar,Roger J. Hajjar,Francesca Stillitano Cardiovascular research(2022)
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Humanized mouse,Phospholamban R14del mutation,CRISPR,Cas9,Ventricular tachycardia,Gene therapy
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