Linkage Analysis Identifies Novel Loci in Early-Onset Alzheimer Disease in Non-Hispanic White Families.

Melissa N Jean-Francois,Margaret A Pericak-Vance,Eder Lucio da Fonseca,Penelope Baez,Temitope Ayodele,Jacob Welch,Kara L Hamilton-Nelson,Eden R Martin,Michael L Cuccaro,Christiane Reitz,Gary W Beecham

PubMed（2021）

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摘要

Several novel linkage EOAD regions have been identified that where not previously identified in known LOAD regions. The identification of these regions may provide information to establish EOAD as a separate disease from Late-onset Alzheimer disease as well as provide therapeutic targets for AD.

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