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MEK Inhibition in a Newborn with RAF1-Associated Noonan Syndrome Ameliorates Hypertrophic Cardiomyopathy but is Insufficient to Revert Pulmonary Vascular Disease

Alessandro Mussa,Diana Carli,Elisa Giorgio,Anna Maria Villar,Simona Cardaropoli,Caterina Carbonara,Maria Francesca Campagnoli, Paolo Galletto, Martina Palumbo, Simone Olivieri,Claudio Isella,Gregor Andelfinger,Marco Tartaglia,Giovanni Botta,Alfredo Brusco,Enzo Medico,Giovanni Battista Ferrero

GENES（2022）

引用 15|浏览28
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关键词
therapeutics,hypertrophic cardiomyopathy,Noonan syndrome,MEK-inhibitor,RASopathies,transcriptomics
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