Quality of life is improved after urethroplasty in women with urethral stricture

INTERNATIONAL UROGYNECOLOGY JOURNAL(2022)

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摘要
Introduction and hypothesis To evaluate the quality of life (QoL) in women who underwent urethroplasty for urethral stricture. Methods Twenty-two women who underwent ventral labium minus graft urethroplasty were included. Patients were assessed with uroflowmetry, urethral caliber and post-voiding residual urine (PVR). American Urological Association (AUA) symptom score, Urogenital Distress Inventory (UDI)-6 and Short Form-36 (SF-36) were used to evaluate QoL. Preoperative values were compared with patients’ last visit data. The cure of the surgery was defined as a maximum flow rate > 15 ml/s in uroflowmetry and no need for any further intervention. Results Median age was 55 (40–66) years. Cure was achieved in 20 (90.3%) patients with median 37 (13–52) months follow-up duration. The median Qmax increased from 4 (0–5) ml/s to 27.5 (8–55) ml/s ( p < 0.001). Median post-void residual volume (PVR) decreased from 52.5 (0–120) ml to 20(0–60) ml ( p = 0.011). Both AUA symptom score [from median 30 (24–35) to 4.5 (0–20), p < 0.001] and AUA-QoL score [from median 5 (4–6) to 0(0–3), p < 0.001] decreased after surgery. Median UDI summary score at the last follow-up was 0 (0–44.4), which was 33.3 (22.2–61.05) at baseline visit. Improvement was observed in all domains except the ‘Energy/Fatigue’ domain of the SF-36. Conclusions Urethroplasty is an effective surgical method to improve patients’ QoL which is impaired because of female urethral stricture.
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关键词
Female urethral stricture, Quality of life, Reconstructive surgery, Urethroplasty
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