Discovery of a Tricyclic Farnesoid X Receptor Agonist HEC96719, a Clinical Candidate for Treatment of Non-Alcoholic Steatohepatitis.
European Journal of Medicinal Chemistry(2021)
关键词
Non-alcoholic steatohepatitis,Farnesoid X receptor agonist,Chemical synthesis,Pharmacokinetic assay,Pharmacological assay,Safety profiling,Drug development
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