miR-277 targets hid to ameliorate Aβ42-mediated neurodegeneration in Drosophila eye model of Alzheimer's Disease.

Prajakta Deshpande,Chao-Yi Chen,Catherine Yeates,Chun-Hong Chen,Madhuri Kango-Singh,Amit Singh

Alzheimer's & dementia : the journal of the Alzheimer's Association（2021）

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摘要

Hereby we provide a mechanism of how mir-277 modulates Aβ42 mediated neurodegeneration by regulating hid transcript levels and demonstrate its neuroprotective role in Aβ42-mediated neuropathology.

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