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硫化氢的神经保护作用研究

International Journal of Immunology(2021)

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Abstract
硫化氢(hydrogen sulfide,H 2S)是继一氧化碳(CO)和一氧化氮(NO)之后的第三种气体传递介质和神经调节剂。硫化氢从抗氧化、抗炎、抗凋亡和自噬等方面起到神经保护作用,在阿尔茨海默病(Alzheimer’s disease, AD)、帕金森病(Parkinson's disease,PD)、创伤性脑损伤(traumatic brain injury,TBI)和脑缺血等神经系统疾病中发挥重要作用。释放H 2S的药物可能为神经系统疾病治疗提供新的思路。
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Key words
Hydrogen sulfide,Alzheimer’s disease,Parkinson's disease,Traumatic brain injury,Cerebral ischemia
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