Prevalence and Prognostic Implications of Moderate or Severe Mitral Regurgitation in Patients with Bicuspid Aortic Valve

•In this international registry of 2,932 patients with BAV, 5.0% had significant MR.•A total of 1.5% had significant primary MR and 3.5% significant secondary MR.•Significant MR was not independently related to outcomes in patients with BAV.•Significant MR not related to AV disease was associated with all-cause mortality.•Significant MR was associated with mortality in patients with significant AR and BAV.