International Session Workshop (IS‐WS)

The association between pregnancy induced hypertension and hypertension in later life by age group:A cross sectional analysis Maiko Wagata, Yasuhiro Kurosawa, Hirotaka Hamada, Michiyo Kurakata, Tetsuro Hoshiai, Hidekazu Nishigori, Masatoshi Saito, Akimune Fukushima, Nobuo Yaegashi, Junichi Sugawara Division of Feto Maternal Medical Science, Tohoku Medical Megabank Organization, Tohoku University, Tohoku University Graduate School of Medicine, Division of Innovation & Education, Iwate Tohoku Medical Megabank Organization, Iwate Medical University Objective To clarify the association between pregnancy induced hypertension(PIH)and hypertension in later life by age group. Methods A cross sectional population based cohort study was conducted from May 2013 to March 2016. Of the 39,379 women between the ages of 20 and 75(mean 59.7±11.3), 33,303 parous women were included in this analysis. A history of PIH was determined by questionnaires, and hypertension was defined as systolic blood pressure>=140mmHg or diastolic blood pressure >=90mmHg or current medication for hypertension. We analyzed the association between history of PIH and hypertension using chi square test. Multivariable logistic regression analysis was also performed to adjust for age, body mass index and drinking status in each age group. Results In total, 1,575(4.7%)women had a history of PIH. The prevalence of hypertension in women with and without a history of PIH was 51.8% and 36.8% respectively(p<0.0001). Women with a history of PIH had higher prevalence of hypertension in all age group. The adjusted odds ratio for hypertension in women with a history of PIH and 95% confidence interval in 30s, 40s, 50s, 60s, and 70s were 3.88(2.08 7.23), 2.30(1.58 3.36), 2.34(1.85 2.97), 1.64 (1.40 1.92)and 2.04(1.52 2.73), respectively. ConclusionWomen with a history of PIH had a higher risk of hypertension in later life and the impact was greater in younger age group. We should recommend health examination and home blood pressure monitoring for women with a history of PIH even after puerperal period.