Dibromination of Cinnamamides with CBr4 under Mild Conditions
Letters in organic chemistry(2022)
摘要
: A novel, mild and efficient protocol to synthesize dibrominated propanamides has been developed. The presented methodology provides several merits, such as easy-to-handle and stable brominated substrate, catalyst-free, additive free and facile experimental operation. The preliminary mechanism study indicated that a free radical pathway might be involved in the presented reaction.
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关键词
Dibromination,cinnamamides,CBr4,dibrominated propanamides,radical reaction,synthesis
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