Altered IL-33/SST2 Axis in Guillain Barre Syndrome and Its Functional Role in Disease Activity

Monojit Debnath,Doniparthi Seshagiri,Madhu Nagappa,Praveen Sharma,Thrinath Mullapudi,Nikhitha Sreenivas,Saikat Dey,Rahul Wahatule,Vijay Kumawat, S. Binu,Sanjib Sinha,Arun Taly

Journal of the neurological sciences（2021）

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摘要

Interleukin −33 (IL-33) and its soluble receptor (sST2) regulate Th1/Th2 immune responses; the altered activity of IL-33/sST2 leads to the development and severity of various immune-mediated diseases. This study is aimed to explore the role of IL-33/sST2 axis in Guillain Barre Syndrome (GBS).

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