Assessment Of Different Pharmacological Activities Of Cayaponia Tayuya (Vell.) Cogn

Phytotherapy is an alternative therapeutic practice incorporated to the Brazilian Health System. Cucurbitaceae family members, including Cayaponia tayuya, are used in folk medicine and related to a wide range of biological activities. In this sense, the aim of this report was to evaluate pharmacological activities of C. tayuya aqyeous extract with in vitro models. In the DPPH assay, it was detected an IC50=153.97 μg/mL, probably beacause of aqueous fraction. The extract was non-toxic to Artemia salina naupii (LC50=1293.76 μg/mL). C. tayuya reduced the number of murine fibroblast cells (L929), however it was non-toxic on concentrations below 125 μg/mL. Moreover, the extract had low capacity to inhibit Acetylcholinesterase. These data suggest that C. tayuya may be a potential candidate as a safe natural product.