Primary Linitis of the Colon is a Rare Tumor

Primary colic linitis is a rare tumor .colonic biopsies are frequently negative. The search for a primitive is imperative, because only its negativity affirms the primary character of the tumor. The endoscopic exploration shows the integrity of the mucosa, with a narrowing lumen or impassable stenosis. The diagnosis is based on particular pathological criteria: submucosal spread and a scirrhous carcinoma with diffuse thickening and hardening of the bowel wall consisted of independent signet ring cells. Immunohistochemistry could help in the differential diagnosis between primary colonic ADK (CK7-; CK20+) and colonic metastasis from gastric linitis (CK 7+, CK 20). In our case, tumor cells were positive for CDX2 (intensive and diffuse marking). Primary colic linitis is a rare but extremely aggressive, diagnosed at a late stage. Lymphatic metastases often found at the time of the diagnosis makes the prognosis very pejorative.