Stable IgG-antibody Levels in Patients with Mild SARS-CoV-2 Infection

T. Åkerlund, K. Zakikhany,C. Lofstrom, E. Lindmark,H. Kallberg,U. Elofsson, K. Cedebrant,E. Nygren, A. Kallin, N. Lagerqvist,P. Nilsson,S. Hober, A. Ridderstad Wollberg, A. Bjørndal

medRxiv（2021）

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摘要

More knowledge regarding persistence of antibody response to SARS-CoV-2 infections in the general population with mild symptoms is needed. We measured and compared levels of SARS-CoV-2 spike- and nucleocapsid-specific IgG-antibodies in serum samples from 145 laboratory-confirmed COVID-19 cases and 324 non-cases. The IgG-antibody levels against the spike protein in cases were stable over the time-period studied (14 to 256 days), while antibody levels against the nucleocapsid protein decreased over time.

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