Common Gene Expression Signature of B-Cells of Waldenström Macroglobulinemia (WM) and IgM Monoclonal Gammopathies of Undetermined Significance (IgM MGUS) Compared to Healthy Subjects

Alessandra Trojani,Barbara Di Camillo,Luca Emanuele Bossi,Antonino Greco,Livia Leuzzi,Alessandra Tedeschi,Anna Maria Frustaci,Marina Deodato,Giulia Zamprogna,Agostina Melluso, Alessia Panzeri,Marco Montillo,Alessandro Beghini,Roberto Cairoli

Blood（2021）

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摘要

We performed a comparative gene expression profiling (GEP) study on B-cells and plasma cells of Waldenström Macroglobulinemia (WM), IgM monoclonal gammopathies of undetermined significance (IgMMGUS), and normal individuals (CTRLs) to identify GEP changes as reliable predictors of progression of IgMMGUS to WM.

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关键词

waldenström macroglobulinemia,igm monoclonal gammopathies,igm monoclonal,igm mgus,b-cells

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