Hyperexcitability and Dysfunction of Cortical Excitation / Inhibition Mechanisms in Migraine: A Paired Pulse TMS Study

Paired-pulse TMS paradigms can be used to test connectivity within the primary motor cortex. Aim of the study was to provide additional information on short intracortical inhibition (SICI) and intracortical facilitation(ICF) using different intensities of the test stimulus (TS) in episodic and chronic migraine(CM, EM) patients.