Long-Term Control of Primary Cerebral ALH Amyloidoma with Focal Radiation Therapy
Advances in radiation oncology(2022)
摘要
Amyloids are depositions of insoluble proteinaceous fibrils with β-sheet secondary structure. Many proteins can form amyloids, including immunoglobulin light chain (AL amyloid) and less frequently, immunoglobulin heavy chain (AH amyloid). AL amyloid deposition is typically associated with AL amyloidosis, a systemic condition often associated with multiple myeloma.1 AL amyloidosis can result in tumor-like accumulations of amyloid called “amyloidomas.” These occur rarely but are most frequent in the respiratory, urinary, and gastrointestinal tracts.
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