Translating Dosimetry of Dibenzo[def,p]chrysene (DBC) and Metabolites Across Dose and Species Using Physiologically Based Pharmacokinetic (PBPK) Modeling

Paritosh Pande,Erin P. Madeen,David E. Williams,Susan R. Crowell,Ted J. Ognibene,Ken W. Turteltaub,Richard A. Corley,Jordan N. Smith

Toxicology and Applied Pharmacology（2021）

引用 3|浏览17

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关键词

Polycyclic aromatic hydrocarbon (PAH),Dibenzo[def,p]chrysene (DBC),Physiologically based pharmacokinetic (PBPK) modeling,Interspecies extrapolation,Internal dose-metrics

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