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    • Supplementary Table from Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges

    Cancer discovery（2021）SCI 1区

    Univ Calif Los Angeles | Univ Calif San Diego | Netherlands Canc Inst | Univ Illinois | Univ Texas MD Anderson Canc Ctr | Halicioglu Data Sci Inst

    Cited 25|Views59
    Abstract
    Supplementary Table from Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges
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    Tumor Targeting
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    Chat Paper
    【要点】：本文研究了外染色体和内染色体BRAF扩增的塑性，探讨其在克服靶向治疗剂量挑战中的作用及机制。
    

    【方法】：作者通过细胞培养、分子生物学技术和生物信息学分析，对BRAF扩增的塑性进行了深入研究。
    

    【实验】：实验在特定细胞系中进行，使用的数据集包括外染色体和内染色体BRAF扩增的基因表达数据，结果显示BRAF扩增的塑性有助于克服靶向治疗剂量限制。