Role of the LRP1-pPyk2-MMP9 pathway in hyperoxia-induced lung injury in neonatal rats.

Ya-Fei Zheng,Hai-Yan Zhu,Wei Wang,Jing-Jing Hu,Tian-Ping Bao,Zhao-Fang Tian

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics（2021）

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摘要

The activation of the LRP1-pPyk2-MMP9 pathway is enhanced in hyperoxia-induced lung injury in neonatal rats, which may be involved in the pathogenesis of bronchopulmonary dysplasia.

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关键词

Hyperoxia,Low-density lipoprotein receptor-related protein 1,Lung injury,Matrix metalloproteinase,Rat

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