Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

Jürgen Brem,Tharindi Panduwawala,Jon Ulf Hansen, Joanne Hewitt,Edgars Liepins,Pawel Donets,Laura Espina,Alistair J. M. Farley,Kirill Shubin,Gonzalo Gomez Campillos,Paula Kiuru,Shifali Shishodia,Daniel Krahn,Robert K. Leśniak, Juliane Schmidt (Adrian),Karina Calvopiña,María-Carmen Turrientes,Madeline E. Kavanagh,Dmitrijs Lubriks,Philip Hinchliffe,Gareth W. Langley,Ali F. Aboklaish,Anders Eneroth,Maria Backlund,Andrei G. Baran,Elisabet I. Nielsen,Michael Speake,Janis Kuka,John Robinson,Solveiga Grinberga,Lindsay Robinson,Michael A. McDonough,Anna M. Rydzik,Thomas M. Leissing,Juan Carlos Jimenez-Castellanos,Matthew B. Avison,Solange Da Silva Pinto,Andrew D. Pannifer,Marina Martjuga,Emma Widlake,Martins Priede,Iva Hopkins Navratilova,Marek Gniadkowski,Anna Karin Belfrage,Peter Brandt,Jari Yli-Kauhaluoma, Eric Bacque,Malcolm G. P. Page,Fredrik Björkling,Jonathan M. Tyrrell,James Spencer,Pauline A. Lang,Pawel Baranczewski,Rafael Cantón,Stuart P. McElroy,Philip S. Jones,Fernando Baquero,Edgars Suna,Angus Morrison,Timothy R. Walsh,Christopher J. Schofield

NATURE CHEMISTRY（2021）

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Drug discovery and development,Lead optimization,Medicinal chemistry,Chemistry/Food Science,general,Analytical Chemistry,Organic Chemistry,Physical Chemistry,Inorganic Chemistry,Biochemistry

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