Synthesis of 2-Aminobenzofurans Via Base-Mediated [3 + 2] Annulation of N-phenoxy Amides with Gem-Difluoroalkenes
Organic chemistry frontiers(2021)
摘要
Efficient metal-free [3 + 2] annulation of N-phenoxy amides with gem-difluoroalkenes has been realized for the assembly of 2-aminobenzofuran derivatives with potent cytotoxicity against cancer cell lines and application potential for DELs.
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