Electrolyte‐Triggered C5‐Selective Trifluoromethylation and Halogenation of 8‐aminoquinoline Derivatives

An efficient electrolyte‐triggered trifluoromethylation and halogenation at C5 position of 8‐aminoquinoline derivatives was developed, affording the C−H functionalization products in moderate to excellent yields. Furthermore, the mild and green reactions had lower energy consumption and shorter times. Most importantly, both transition‐metal catalysts and oxidants were avoided.