An Overview Of Hypoglycemia In Children Including A Comprehensive Practical Diagnostic Flowchart For Clinical Use
FRONTIERS IN ENDOCRINOLOGY(2021)
摘要
Hypoglycemia is the result of defects/impairment in glucose homeostasis. The main etiological causes are metabolic and/or endocrine and/or other congenital disorders. Despite hypoglycemia is one of the most common emergencies in neonatal age and childhood, no consensus on the definition and diagnostic work-up exists yet. Aims of this review are to present the current age-related definitions of hypoglycemia in neonatal-pediatric age, to offer a concise and practical overview of its main causes and management and to discuss the current diagnostic-therapeutic approaches. Since a systematic and prompt approach to diagnosis and therapy is essential to prevent hypoglycemic brain injury and long-term neurological complications in children, a comprehensive diagnostic flowchart is also proposed.
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关键词
neonatal hypoglycemia, childhood hypoglycemia, inborn errors of metabolism, endocrine hypoglycemia, glucose homeostasis, congenital hyperinsulinism
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