P09.06 CNS Metastasis Negatively Impact Overall Survival of Non-Small Cell Lung Cancer (NSCLC) Patients Treated with Immune Checkpoint Inhibitors

Lung cancer is the leading cause of cancer-related death worldwide. Unfortunately, most of patients are diagnosed with advanced NSCLC. Stage, performance status and central nervous system (CNS) metastases have been recognized as prognostic factors. Immune checkpoint inhibitors (ICI) have greatly improved survival outcomes and can result in deep and durable antitumor responses in lung cancer but survival rates vary among patients with metastatic disease.