A universal pocket in fatty acyl-AMP ligases ensures redirection of fatty acid pool away from coenzyme A-based activation.

Gajanan S Patil,Priyadarshan Kinatukara,Sudipta Mondal,Sakshi Shambhavi,Ketan D Patel,Surabhi Pramanik,Noopur Dubey,Subhash Narasimhan,Murali Krishna Madduri,Biswajit Pal,Rajesh S Gokhale,Rajan Sankaranarayanan

eLife（2021）

Cited 5|Views28

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Key words

E. coli,acyl carrier protein,biochemistry,chemical biology,coenzyme A,fatty acids,fatty acyl-AMP ligases,nonribosomal peptide synthetases,polyketide synthases

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