Guidelines For The Prevention And Therapy Of Glucocorticoid-Induced Osteoporosis

AimTo review the literature and provide guidelines for the prevention and treatment of glucocorticoid induced osteoporosis.MethodsReview of all randomized controlled trials studying prevention or treatment of glucocorticoid-induced osteoporosis.ResultsThere is ample evidence in the literature demonstrating that use of supraphysiologic doses of glucocorticoids can lead to significant amounts of bone loss as early as the first 3 to 6 months of use, with devastating consequences. While our understanding of the mechanisms leading to glucocorticoid-induced bone loss is limited, effective therapy for prevention and management is available.ConclusionCurrent data show that bisphosphonate therapy is the treatment of choice for the prevention and management of glucocorticoid-induced osteoporosis.