(2s*,4s*)-4-[(E)-(2,2-Dimethylhydrazono)Methyl]-6-Methoxy-4-Methyl-2-[(E )-Styryl]-1,2,3,4-Tetrahydroquinoline

The Povarov reaction of p-anisidine, cinnamaldehyde and methacrolein dimethylhydrazone afforded a 1,2,3,4-tetrahydroquinoline derivative bearing 2-styryl, 4-methyl and 4-dimethylhydrazono substituents in a fully diastereoselective fashion. This is the first example of the combination of a type I aza-vinylogous Povarov reaction and a type II vinylogous Povarov reaction in the same process.