Methyl Gallate As An Antioxidant And Anti-Hiv Agent
HIV/AIDS: OXIDATIVE STRESS AND DIETARY ANTIOXIDANTS(2018)
摘要
Methyl gallate is an antioxidant found in a great variety of plant species including some edible beans and also mushrooms. It protects a diversity of cells including liver cells, kidney cells, heart cells, neuronal cells, and fat cells from oxidative stress induced by chemicals such as hydrogen peroxide. It upregulates antioxidant enzymes. It inhibits three key enzymes crucial to the HIV life cycle including reverse transcriptase, protease, and integrase. Methyl gallate inhibits HIV-1 replication in pseudovirus-infected TZM-BL cells.
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关键词
Antioxidant, HIV integrase, HIV protease, HIV reverse transcriptase, Methyl gallate
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