Fluorescent Chemosensor Based On The Pyrene@2 Beta-Cyclodextrin Complex: Response To Aromatic Amino Acids

The applicability of the pyrene@2 beta-cyclodextrin complex as a fluorescent chemosensor for aromatic amino acids has been studied by fluorescence spectroscopy. For the first time, it has been that the sensitivity of the complex to the implementation of D-enantiomers into its cavity is higher in comparison with the L-enantiomers of aromatic amino acids. Quantum-chemical calculations confirmed that the binding of the D-enantiomers of aromatic amino acids with P@2 beta CD is characterized by a greater energy of complexation in comparison with the L-enantiomers.