Antimicrobial and Antioxidant Screening of Flueggea Virosa

The antimicrobial and antioxidant activity of Flueggea virosa (Roxb. ex Willd.) Voigt was assessed by preparing extracts in petroleum ether, chloroform, methanol and water. By using agar well diffusion and dilution method the Zone of Inhibition and MIC assay was measured. Maximum activity showed by aqueous extract of leaf of F. virosa against S. aureus, i.e. 45 +/- 1.0 mm. The bark extract had exhibited greater potential as compared to leaf against respective strain. The antifungal assessment had revealed that the leaf and bark extracts had revealed satisfactory potential. Methanolic extract of bark of F. virosa showed the highest antifungal activity against A. oryzae, i.e 15.6 +/- 0.5 mm. The highest total phenolic contents (TPC) content was provided by methanolic extract of leaf of F. virosa, i. e. 3029.25 GAE mu g/mL and wide range of flavonoid con tents. The significant DPPH free radical scavenging was exhibited by methanolic extract of bark whereas the value of percentage of bound iron ranging from -60.84 +/- 0.9 to 56.75 +/- 1.0. The ABTS radical cation was range in 5.79 +/- 1.0-10.56 +/- 0.7 mM of TE and maximum capacity was displayed by the aqueous extract of bark.