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Robust Patient-Derived Xenografts of MDS/MPN Overlap Syndromes Capture the Unique Characteristics of CMML and JMML

BLOOD(2017)

引用 29|浏览6
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摘要
Key Points Genetically accurate xenografts of CMML are achievable with near 100% frequency in NSGS mice. Robust human engraftment and overt phenotypes of CMML and JMML xenografts here facilitate preclinical therapeutic evaluation in vivo.
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