Frequency and Predictors of Decompressive Craniectomy in Ischemic Stroke Patients Treated by Mechanical Thrombectomy in the ETIS Registry.

G. Adwane,B. Lapergue,M. Piotin,B. Gory,R. Blanc,A. Consoli,G. Rodesch,M. Mazighi,M. Kyheng,J. Labreuche,F. Pico

Revue Neurologique（2023）

Cited 0|Views25

Abstract

Background and aims. - Mechanical thrombectomy (MT) for patients with acute ischemic stroke (AIS) is usually performed in a comprehensive stroke center with on -site neurosurgical expertise. The question of whether MT can be performed in a primary stroke center without a neurosurgical facility is debated. In this context, there is a need to determine the frequency, delay and predictors of neurosurgical procedures in patients treated by MT. This study aims to determine these factors. Methods. - In total, 432 patients under 60 years old, diagnosed with an acute ischemic stroke with a large vessel occlusion and treated by MT between January 2018 and December 2019 in six French stroke centers, were selected from the French clinical registry ETIS. Univariate and multivariate logistic regression models were used to identify predictive factors for decompressive craniectomy. Results. - Among the 432 included patients, 43 (9.9%) patients with an anterior circulation infarct underwent decompressive craniectomy. Higher admission NIHSS (OR: 1.08 [95% CI: 1.02-1.16]), lower ASPECT (OR per 1 point of decrease 1.53 [1.31-1.79] P < 0.001) and preadmission antiplatelet use (OR: 3.03 [1.31-7.01]) were independent risk factors for decompressive craniectomy. The risk of decompressive craniectomy increases to more than 30% with an ASPECT score < 4, an NIHSS > 16, and current antiplatelet use. Conclusion. - In this multicenter registry, 9% of acute ischemic stroke patients ( < 60 years old) treated with MT, required decompressive craniectomy. Higher NIHSS score, lower ASPECT score, and preadmission antiplatelet use increase the risk of subsequent requirement for decompressive craniectomy. (c) 2023 Elsevier Masson SAS. All rights reserved.

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Key words

Malignant cerebral infarct,Decompressive craniectomy,Endovascular treatment

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