Rare Variant Analysis in Eczema Identifies Exonic Variants in DUSP1, NOTCH4 and SLC9A4

Sarah Grosche,Ingo Marenholz,Jorge Esparza-Gordillo,Aleix Arnau-Soler,Erola Pairo-Castineira,Franz Rüschendorf,Tarunveer S. Ahluwalia,Catarina Almqvist,Andreas Arnold,Hansjörg Baurecht,Hans Bisgaard,Klaus Bønnelykke,Sara J. Brown,Mariona Bustamante,John A. Curtin,Adnan Custovic,Shyamali C. Dharmage,Ana Esplugues,Mario Falchi,Dietmar Fernandez-Orth,Manuel A. R. Ferreira,Andre Franke,Sascha Gerdes,Christian Gieger,Hakon Hakonarson,Patrick G. Holt,Georg Homuth,Norbert Hubner,Pirro G. Hysi,Marjo-Riitta Jarvelin,Robert Karlsson,Gerard H. Koppelman,Susanne Lau,Manuel Lutz,Patrik K. E. Magnusson,Guy B. Marks,Martina Müller-Nurasyid,Markus M. Nöthen,Lavinia Paternoster,Craig E. Pennell,Annette Peters,Konrad Rawlik,Colin F. Robertson,Elke Rodriguez,Sylvain Sebert,Angela Simpson,Patrick M. A. Sleiman,Marie Standl,Dora Stölzl,Konstantin Strauch,Agnieszka Szwajda,Albert Tenesa,Philip J. Thompson,Vilhelmina Ullemar,Alessia Visconti,Judith M. Vonk,Carol A. Wang,Stephan Weidinger,Matthias Wielscher,Catherine L. Worth, Chen-Jian Xu,Young-Ae Lee

Nature Communications（2021）

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关键词

Atopic dermatitis,Genetic predisposition to disease,Genome-wide association studies,Rare variants,Skin diseases,Science,Humanities and Social Sciences,multidisciplinary

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