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Inclusion of the Inducible Caspase 9 Suicide Gene in CAR Construct Increases Safety of CAR.CD19 T Cell Therapy in B-Cell Malignancies.

Marika Guercio,Simona Manni,Iolanda Boffa,Simona Caruso,Stefano Di Cecca,Matilde Sinibaldi,Zeinab Abbaszadeh,Antonio Camera,Roselia Ciccone,Vinicia Assunta Polito,Francesca Ferrandino,Sofia Reddel,Maria Luigia Catanoso,Emilia Bocceri,Francesca Del Bufalo,Mattia Algeri,Biagio De Angelis,Concetta Quintarelli,Franco Locatelli

Frontiers in immunology（2021）

引用 16|浏览48
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关键词
chimeric antigen receptor (CAR T),CD19,suicide gene,immunotherapy,B-cell Acute Lymphoblastic Leukemia
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