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Mechanistic Modeling of Placental Drug Transfer in Humans: How Do Differences in Maternal/Fetal Fraction of Unbound Drug and Placental Influx/Efflux Transfer Rates Affect Fetal Pharmacokinetics?

FRONTIERS IN PEDIATRICS(2021)

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关键词
physiologically based pharmacokinetics (PBPK), placental drug transfer, maternal-fetal, pregnancy, mechanistic modeling
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